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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TOB1
All Species:
17.58
Human Site:
S236
Identified Species:
55.24
UniProt:
P50616
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50616
NP_005740.1
345
38155
S236
L
Y
G
L
G
L
G
S
Q
Q
Q
P
Q
Q
Q
Chimpanzee
Pan troglodytes
XP_523795
697
76786
S588
L
Y
G
L
G
L
G
S
Q
Q
Q
P
Q
Q
Q
Rhesus Macaque
Macaca mulatta
XP_001095282
704
76360
S595
L
Y
G
L
G
L
G
S
Q
Q
Q
P
Q
Q
Q
Dog
Lupus familis
XP_849289
316
34141
L218
H
K
S
L
S
L
S
L
H
S
L
N
F
I
A
Cat
Felis silvestris
Mouse
Mus musculus
Q61471
363
40214
S238
L
Y
G
L
G
L
G
S
Q
Q
Q
P
Q
P
Q
Rat
Rattus norvegicus
Q8R5K6
365
40443
S238
L
Y
G
L
G
L
G
S
Q
Q
Q
P
Q
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511345
341
37099
G236
L
Y
G
L
G
L
G
G
Q
P
P
P
P
P
P
Chicken
Gallus gallus
Frog
Xenopus laevis
P40745
233
26927
H141
E
K
A
T
S
D
Y
H
S
G
T
S
S
D
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.2
48.1
55.3
N.A.
91.7
91.7
N.A.
89.8
N.A.
24
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
49.5
49
69.8
N.A.
93.6
94.2
N.A.
91.8
N.A.
39.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
93.3
93.3
N.A.
60
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
93.3
93.3
N.A.
60
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
13
0
0
0
0
0
0
0
13
0
% D
% Glu:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% F
% Gly:
0
0
75
0
75
0
75
13
0
13
0
0
0
0
0
% G
% His:
13
0
0
0
0
0
0
13
13
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% I
% Lys:
0
25
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
75
0
0
88
0
88
0
13
0
0
13
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
13
13
75
13
38
13
% P
% Gln:
0
0
0
0
0
0
0
0
75
63
63
0
63
38
63
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
13
0
25
0
13
63
13
13
0
13
13
0
0
% S
% Thr:
0
0
0
13
0
0
0
0
0
0
13
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
75
0
0
0
0
13
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _